Computational Systems Biology
Research in the Ruppin Laboratory is focused on computational systems biology. This is the study of large-scale biological systems with the aid of computers and computations.
Our laboratory is a world leader in the study of metabolism – the domain of living cells responsible for energy turnover and the basic building blocks of life. As part of this research, the lab studies in-silico reconstructions of metabolic models of certain bacteria and plants, with the aim of predicting genetic manipulations that could enhance the production of bio-fuels in these organisms. Such computational methods hold considerable promise in achieving these objectives, as they have already proven their ability for enhancing the production of many other sought-after biochemical products.